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    New Disease

    Brain injury causes a loss of smell and taste

    traumatic brain Brain injury causes a loss of smell and tasteThe sense of taste and smell can be lost or impaired after head trauma, according to a new study by scientists at the University of Montreal, Lucie Bruneau Rehabilitation Centre and the Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal. Published in the journal Brain Injury, the survey found that mild to severe traumatic brain injury could cause loss of smell.

    “The study clearly shows that olfactory deficits may occur in mild traumatic brain injury, and moderate and severe head trauma patients,” said study co-author and neuropsychologist Maurice Ptito, a professor in the School of University of Montreal optometry. “We also found that patients with frontal lesions were more likely to olfactory dysfunction.

    The research team recruited 49 people with traumatic brain injury (73 percent of men with a mean age of 43) who completed a questionnaire and underwent two tests to measure the loss of smell the smell. The result: 55 percent of subjects had an impaired sense of smell, while 41 percent of the participants were aware of their olfactory deficit.

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    Slowing down the brakes of the immune system may contribute to the improvement of therapeutic vaccines for HIV

    therapeutic HIV Slowing down the brakes of the immune system may contribute to the improvement of therapeutic vaccines for HIVLike a wayward driver slammed the brakes, a special class of T cells may limit the effectiveness of therapeutic vaccines for HIV by slowing the immune system too soon, the report of the University of Pittsburgh researchers at Health Sciences latest issue of PLoS ONE. Their study, the first to examine the role of regulatory T cells in therapeutic vaccines against HIV, could help researchers improve the effectiveness of these vaccines in the development of methods to prevent the brake mechanism of these cells.

    Regulatory T cells (Treg) are essential because they prevent the immune system turns against itself by suppressing the immune response. Without the braking action of Treg, autoimmune disease can thrive. But if these cells are closing the immune response of a therapeutic vaccine had the opportunity to boost immunity against HIV?

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    New gateway to treat leukaemia and other cancers

    leukaemia blood cancer New gateway to treat leukaemia and other cancers Canadian researchers have discovered a previously hidden channel to attack leukemia and other cancer cells, according to a new study published in the Journal of Biological Chemistry. The results of the University of Montreal, Maisonneuve-Rosemont Hospital and Laval University may change doctors treat cancer patients.

    “We found a door, which is present in all human beings, which enables anti-cancer agents such as bleomycin to enter the body so they can reach and attack the leukemia cells,” says lead author Dindial Ramotar , a professor at the Faculty of Medicine of the University of Montreal and a research affiliate at the Maisonneuve-Rosemont.

    Dr. Ramotar has begun to test his theory ten years ago with the help of yeast, which is remarkably similar to human cells. “Our discovery has increased in this model system for human cells and will soon come to bed due to the therapy of translation, he said.” We are about to test patients. ”

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    Well tolerated specific nodal radiotherapy after surgery in women with breast cancer in early stage

    early breast cancer Well tolerated specific nodal radiotherapy after surgery in women with breast cancer in early stage In patients with early breast cancer, giving radiotherapy to the lymph nodes behind the breastbone and above the clavicle is well tolerated after a mastectomy or a lumpectomy, a radiation oncologist to delegates at the Seventh European Cancer Conference Breast (EBCC7) Saturday, March 27. Women at high risk of developing breast cancer likely benefit from additional nodal radiation therapy, Dr. Philip Poortmans, Dr. Bernard Verbeet Instituut Tilburg, the Netherlands, and member of the European Organization for Research and Treatment of Cancer (EORTC ) Radiation Oncology Group, said. The first results of the 4004-patient multicenter study carried out by radiation therapy and breast cancer groups EORTC (46 institutions in 13 countries) shows no evidence of increased toxicity in the heart of three years of follow-up among patients receiving additional lymph node radiotherapy.

    Patients were followed for many years to see if the specific radiation of lymph nodes can cause long term damage of the heart or lungs, the side effects associated with radiation therapy for breast cancer.

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    Maintaining normal daily routine for a better quality of sleep in older adults

    sleep problem Maintaining normal daily routine for a better quality of sleep in older adults A study in the April 1 issue of the journal SLEEP found that routine maintenance was associated with a reduction of insomnia and improves sleep quality in older people living in a retirement community.

    The results of regression analysis indicate that the increased stability of the daily routine predicts poor sleep time, greater efficiency and improved sleep quality sleep. Stability in basic activities as bathing, dressing and eating was most strongly associated with sleep quality and stability of the instrumental activities such as shopping, using public transport and medical controls.

    The authors suggest that the pace of the routine of life can be characterized by stability over time, frequency and duration of daily activities such as watching TV or reading a book. It is also possible to identify trends in the regular weekly activities such as cleaning, exercise and social commitments.

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    Track a result of motor neuron disease

    neuron disease Track a result of motor neuron disease Researchers have discovered a genetic mutation associated with this typical motor neuron disease or amyotrophic lateral sclerosis, which has a pathological effect similar to certain genetic mutations have shown in previous studies. Ultimately, researchers hope that understanding what causes motor neuron disease (MND) will lead to new ways of treatment.

    MDN is a progressive neurodegenerative disease that attacks the upper and lower motor neurons. The degeneration of motor neurons causes weakness and atrophy of muscles, causing increasing loss of mobility in the limbs, difficulty speaking, swallowing and breathing.

    The new research, published today in the journal Proceedings of the National Academy of Sciences and conducted by researchers from Imperial College London, provides strong additional evidence that genetics is a disease caused by the protein reconstituted in motor neurons, cells that help control muscle movement.

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    New inexpensive way to predict Alzheimer’s disease

    Alzheimer Disease New inexpensive way to predict Alzheimers disease The capacity of your brain to information is a reliable predictor of Alzheimer’s disease may be cheap and easy to test, according to scientists. “We have developed a performance evaluation of low-cost index can anyone Alzheimer’s disease in its early stages,” said Michael Wenger, associate professor of psychology at the University of Pennsylvania. “Looking (information) processing capacity, which can detect changes in the progression of mild cognitive impairment (MCI).”

    MCI is a condition that affects language, memory and mental functions. Is different from the ordinary mental deterioration associated with aging and is a likely precursor of Alzheimer’s disease more severe. MCI and Alzheimer’s disease are related to a decrease in the volume of the hippocampus, the brain region responsible for long-term memory and spatial reasoning.

    MRI – magnetic resonance imaging – are the most reliable and direct detection of atrophy of the hippocampus and the diagnosis of MCI. But for many, the procedure is not available or too expensive.

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    Thyroid condition increases the risk of stroke in young adults

    stroke risk on young adult Thyroid condition increases the risk of stroke in young adults Young adults with hyperthyroidism face a 44 percent risk of stroke compared with those with normal thyroid function, according to a study published in Stroke, Journal of the American Heart Association.

    “Strokes of undetermined cause accounts for between one third and one-quarter of all ischemic strokes among young people,” said Ching-Herng Lin, Ph.D., lead study author and professor at the School of care management Health, Faculty of Medicine Taipei Medical University, Taipei, Taiwan. “To the best of our knowledge, hyperthyroidism has not been considered a risk factor for stroke in the group 18 to 44 years.”

    Hyperthyroidism, also known as overactive thyroid is a common endocrine disorder that affects approximately 0.5 percent (1 in 200 people) to 2 percent (1 to 50) of the world’s population, including a large group of young adults, said Lin. This condition causes an overproduction of thyroid hormone, which speeds up the metabolism and causes symptoms such as sweating, weight loss, diarrhea and nervousness.

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    Potential new target for the treatment of hepatitis C

    hepatitis c Potential new target for the treatment of hepatitis C A team of scientists including the University of Utah, researchers found that the binding of a potent inhibitor of hepatitis C virus (HCV) for the virus’s genetic material causes a significant change in conformation that can adversely affect the ability of the virus to replicated. This discovery, published in the March 29 edition of the first acts of the National Academy of Sciences, offers a new potential target for the design of the structure on the basis of new treatments for hepatitis C.

    Hepatitis C is a major public health problem affecting 170 million people worldwide, with 2 to 3 million new cases diagnosed each year. In the U.S., HCV infection is the leading cause of liver cancer and liver transplantation, killing about 10,000 people each year. Currently, the most effective treatment for hepatitis C is an agent called pegylated interferon, which is often associated with an antiviral drug called ribavirin.

    “The available therapies for hepatitis C have limited effectiveness, with less than 50 percent of an answer,” said Darrell R. Davis, Ph.D., lead author and professor and interim chair of medical chemistry and biochemistry professor at the University of Utah. “However, small molecules that inhibit viral replication have been reported and represent potential opportunities for new HCV treatments more effective.”

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